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The Proteomis report

Introduction

This page is a summary, in simple terms, of how the Proteomis report is produced, the meaning of the various documents submitted to the doctor and the patient, the presentation of the report structure and finally how it can help with diagnosis and decisions regarding treatment.

The Proteomis report

Unlike usual blood tests, the Proteomis does not aim to see if the patient's blood contains an abnormal amount of certain simple, well defined substances or cells; on the contrary it shows the reactions of all serum proteins through the use of fifty tests including analysing the spectrum of acid glycoprotein, immunoglobulin as well as 'broad' tests - for each test, the laboratory adds another chemical to the blood serum.

The balance between the serum proteins ('the key to our black box') is the starting point of this series of tests. By adding different reagents, the electro colloidal balance of the serum is, at each stage, subjected to another test. Thus, the measurement of each test renders another group of about 500,000 serum proteins visible. The collected results are then compared to statistical norms that have been calculated using a vast database of registered analyses. The CEIA's database already contains hundreds of thousands of records. Thanks to the huge number of records, calculating the degree of positive or negative deviations of a test is extremely reliable.

How can the Proteomis report allow us to better see our can see internal biological activity?

The documents provided are of two types: a table listing the chemical names of the reagents, the numerical result of each individual reaction expressed in OD (optical density or 'unit BCD') along with the range of normality for each test established by the laboratory. The second document is a graph.

Each test is named after the chemical reagent used. For example: 'copper acetate 553 UN BCD test' means that when the laboratory added copper acetate to the serum of this patient, a biochemical reaction was created (flocculation) expressed by UN BCD It means there is no copper acetate in the patient's serum! Surnames used such as Takata, Burstein and Kunkel, are the names of the authors of the relevant tests. They also refer to some chemical reagents (e.g. Takata = mercuric chloride). The range between the lower limit and the upper limit is a guideline - it's a legal requirement for test results. The graphic chart provides the most useful information.

On the table of results, the tests are grouped into five 'families' according to the laboratory's system: the 'acid' tests, the 'basic' tests (chemical opposite of 'acid'), 'lipid' tests (meaning 'neutral' lipids or fats that don't react in an acid or basic manner) and finally 'broad' tests. This means that an 'acid' test (for example the copper acetate test) causes 'acid' protein precipitation of the serum. A 'basic' test (for example the Kunkel zinc sulphate test) does the same with the 'basic' proteins, a 'neutral' test reacts with lipoproteins while a 'broad' test is characterized by a mixture proteins from the other three categories.

In the graph, each test is shown under its family colour: green for acid tests, red for neutral lipoprotein, blue for basic tests and violet for broad tests.

The same goes for the fifth family of tests (in gray), entitled 'proteinogram': the values ​​contained therein are different to the aforementioned tests. They do not refer to these tests or tests on serum, but rather to quantity determinations. For this family, the laboratory uses a classification of serum proteins also used in conventional blood tests: globulins alpha1, alpha2, beta and gamma. Using these values, a few other characteristics are calculated (e.g. S/G = the ratio between small serines and large serum globulins). The flocculation bar does not really belong here, this figure being the arithmetic mean of all the response values ​​in the four main categories.

The entire laboratory analysis is printed on the laboratory's letterhead.

The graphic chart

The laboratory results are converted into graphic form, the serum colloid in the form of a 'V' as a descriptive mechanism for the body. This is based on the data stored in the computer so as to arrange tests in order of decreasing deviation: this visualization allows us to accurately see if the score of a test is perfect, too low or too high (and to what extent).

Armed with these criteria, we are able to assess the quantitative deviations on the report.

But we also use qualitative standards: different groups of tests, identifiable by their colour, reflect the degree of activity of the relevant sections of our biological activity. Schematically, green glycoprotein tests are linked to our 'first line of defense', the red lipid tests to our 'supply, management and control' systems, the blue basic tests analyse the immunity of our complex hormonal balance and the broad violet tests analyse our immune memory. The order as well as the position of these test families and the tests within a family help us to determine which families (or groups of) show an abnormal score.

But what is the meaning of these different categories and colours? We'll try to give you an overview in the table below.

Structure of the CEIA curve

Explanation of parameters

The glycoprotein parameters (green)

Green settings are the barometer of our first line of defense, which has two important features: it is a cell-mediated defense (our white blood cells are part of this); it is non-specific and is activated regardless of the type of attack: microbes, virus, wounds, poisoning, etc. This biological activity takes place in our connective tissue, which is like a mesh that binds all of our organs and cells. This is why it's called the 'basic matrix control system'.

Left: A decrease in green settings reveals a weakening of first line of defense; the basic control system is compromised, under stress, clogged and overloaded. The purification function is weakened. The most common complaint is fatigue.

Right: In the event of reactivation of this basic control system, we have seen the appearance of inflammatory conditions - the green parameters therefore increase. Inflammation is therefore not the disease in itself, but rather a defence mechanism! Inflammation 'hunts down' the disease, so to speak. However, inflammation that is markedly intense or lasts a long time is abnormal and is a sign of a cause or a persistent problem.

Lipid parameters (red)

The red parameters refer to all body functions that are related to lipids (fats): this system is like a 'waterfall'.  It begins with food consumption, its absorption (at an intestinal and pancreatic level), processing (liver), its dissemination and distribution (blood vessels) and, last but not least, the level of consumption. Experiments have shown that all aspects of the nervous system play an important role: how fats are metabolized in our body is not just a question of cholesterol levels.

Left: Unfortunately, a low score in lipid tests cannot not be corrected by a change in eating habits; it invariably indicates that all aspects of the nervous system are compromised and it's a common manifestation of many chronic diseases - including chronic fatigue syndrome.

Right: dietary issues are always involved in lipid tests where the score is too high. However, where a health issue is found may vary: digestive system, liver, blood circulation, nervous system.

The immunoglobulin parameters

The blue parameters are a measure of the 'smart' functions that govern our biological balance. We use the word 'smart' because they're only found in higher animal species and human beings are mammals. Higher animal species have an immune memory - our equivalent of files backed up on a computer hard drive. The blue parameters, therefore, relate primarily to immunoglobulins (IG), being our exemplary 'memory proteins'. But the violet parameters also play in important role in this family of immunizing agents. To put it simply, blue IG tests deal with our 'internal' code - hormonal functions are one (particularly visible in women) and hereditary predispositions are the other.

Left: A low score blue test reveals hormonal disturbances and/or a problem with an inherited factor.

Right: Reports where blue the parameters (and often the violet tests) are increased, may show extreme deviations: this kind of result is characteristic of so-called autoimmune diseases (ranging from allergies to AIDS to rheumatism).

Broad tests

Violet parameters or broad tests cover an assorted family of proteins. Their colour means they have been analysed by the laboratory. In other words, they are proteins which appear under the reactive 'violet' label, but which come from the entire spectrum - acid, alkaline and neutral. We can, however, use them as markers of our biological balance: some violet parameters are always included in a family of other parameters (e.g. uranyl nitrate = 'blue') while others may indicate a change depending on the family they join (e.g. the result of a change in sodium phosphotungstate in a blue or red test). The other families also contain some exceptions, as is the case for biological law in general. The main characteristic of violet tests resides in their link to immunoglobulin (IG) or memory proteins, meaning they work in unison with blue tests, except that violet tests concern immune memory related to an external source (endogenous or internal = blue, exogenous or external = violet). Hence the extremely important interaction that the body has with the outside world - such as the intestine (which has a potential immunocompetent surface of 300m²).

Left: lower violet parameters reveal an acquired immune system weakness, often accompanied by the disruption of other intestinal functions (poor absorption of fats, food intolerances).

Right: in the case of a large increase in IG violet and blue tests, the risk of an autoimmune disease is significant. With smaller deviations, it's usually the intestine's immunity which is compromised. Uniquely violet immunoglobulins are the ones our immune system produces in the greatest quantity: their action is to more or less literally 'add weight'. The conclusion is that there's a link with diseases that have 'hardening tendencies' such as sclerosis.

Summary...

To clarify and sum up, the Proteomis report was developed in order to prescribe, with computer-based assistance, individualised and controlled herbal remedies. The goal and purpose of the assessment is to select, from the wide range of biological medicines available, a treatment that is tailored to patients' individual needs. To reach this goal, more than 1,000 plants and metal salts were investigated. During each test even the slightest deviation of these substances was carefully recorded. The result is a computerised data system capable of performing complex calculations that can provide theoretically optimal remedies for each patient report. An interpretation of the results, according to the pathology and the diagnosis, is subsequently undertaken. Many doctors are now benefitting from this diagnostic option. They use the report, along with their medical expertise, to determine treatments from a list of available options. After the patient has a follow-up test, they can evaluate and, if necessary, adjust the treatment. It goes without saying that the test and conventional approaches are perfectly reconcilable - it all depends on the doctor's mindset.

We mustn’t lose sight of the fact that CEIA analyses were originally designed to offer therapeutic help by taking advantage of computer technology. Most patients find this to be an interesting factor.

The system first of all provides an automated record. The effects of each remedy (from a list of more than 1,000 plants and minerals) on the deviations of each distinctive test have been carefully recorded. By applying complex calculations, the IT center at CEIA is able to offer, for each record produced, a list of theoretically optimal remedies. For this purpose, it selects the tests with the most deviant results. Each report comes with a recommendation to use one or more herbal, mineral and aromatic remedies. This is a personalised selection that depends on the observed deviations. It would be unwise to claim that this 'prescription' can guarantee full recovery. It is up to the doctor to assess the report as part of an overall treatment strategy, to talk with the patient and to take responsibility for any treatment plan.

Further down the line, CEIA developed a number of typical biological drugs (homeopathic treatments for example) that are pertinent to single tests or test groups and which, where appropriate, may be prescribed. This is often necessary for test results listed on the left - the results which indicate that the body needs help or a boost.

Finally, the CEIA report requires collaboration between medical practitioners: bearing in mind the wide range of bio therapeutics, natural medicines ('evidence based' medicine, to coin an appropriate German phrase) and allopathic drugs used in conventional medicine. This approach allows for a more specific and occasional use of remedies that are not administered due to subjective evaluations or superficial symptoms.